Chemical Biology

DescriptionAlkyne modified lysine that has been shown to be incorporated site-specifically into recombinant proteins.

DescriptionPhotoactivatable rhodamine derivative functionalized with a PEG azide. The azide functionality can be used to conjugate this caged rhodamine to alkyne or cycloalkyne containing compounds or biomolecules using the azide-alkyne

DescriptionPhotoactivatable rhodamine derivative functionalized with a PEG azide. The azide functionality can be used to conjugate this caged rhodamine to alkyne or cycloalkyne containing compounds or biomolecules using the azide-alkyne

DescriptionCatalyst employed in the cycloaddtion of azides with acetylenes giving exclusively the 1,5-disubstitutedtriazoles in contrast to the 1,4-regiochemistry commonly observed with copper catalysis. Ruthenium catalysis also enables the use of

DescriptionCatalyst employed in the cycloaddtion of azides with acetylenes giving exclusively the 1,5-disubstitutedtriazoles in contrast to the 1,4-regiochemistry commonly observed with copper catalysis. Ruthenium catalysis also enables the use of

DescriptionCatalyst employed in the cycloaddtion of azides with acetylenes giving exclusively the 1,5-disubstitutedtriazoles in contrast to the 1,4-regiochemistry commonly observed with copper catalysis. Ruthenium catalysis also enables the use of

DescriptionPhoto-activatable sterol probe for the bioorthogonal tagging and enrichment of sterol-binding biomolecules. This sterol probe contains an intact steroid core structure bearing a diazirine UV-activatable cross-linking group, as well as an

DescriptionProtein degrader builiding block Pomalidomide-C6-CO2H enables the synthesis of molecules fortargeted protein degradation andPROTAC (proteolysis-targeting chimeras) technology. This conjugate contains a Cereblon (CRBN)-recruiting ligand

DescriptionProtein degrader builiding block Pomalidomide-C6-PEG1-C3-PEG1-butyl azide enables the synthesis of molecules fortargeted protein degradation andPROTAC (proteolysis-targeting chimeras) technology. This conjugate contains a Cereblon

DescriptionProtein degrader builiding block Pomalidomide-C6-PEG1-C3-PEG1-Butyl Iodide enables the synthesis of molecules fortargeted protein degradation andPROTAC (proteolysis-targeting chimeras) technology. This conjugate contains a Cereblon

DescriptionProtein degrader builiding block Pomalidomide-C6-PEG3-butyl alkyne enables the synthesis of molecules fortargeted protein degradation andPROTAC (proteolysis-targeting chimeras) technology. This conjugate contains a Cereblon

DescriptionProtein degrader builiding block Pomalidomide-C6-PEG3-butyl amine (HCl salt) enables the synthesis of molecules fortargeted protein degradation andPROTAC (proteolysis-targeting chimeras) technology. This conjugate contains a Cereblon