Chemical Biology

DescriptionProtein degrader builiding block (S,R,S)-AHPC-PEG4-NH2(HCl salt) enables the synthesis of molecules fortargeted protein degradation and PROTAC (proteolysis-targeting chimeras) technology. This conjugate contains a von Hippel-Lindau

DescriptionProtein degrader builiding block (S,R,S)-AHPC-PEG5-Alkyne enables the synthesis of molecules fortargeted protein degradation andPROTAC (proteolysis-targeting chimeras) technology. This conjugate contains a von Hippel-Lindau

DescriptionProtein degrader builiding block (S,R,S)-AHPC-PEG5-azide enables the synthesis of molecules fortargeted protein degradation andPROTAC (proteolysis-targeting chimeras) technology. This conjugate contains a von Hippel-Lindau

DescriptionProtein degrader building block (SRS)-AHPC-PEG5-NH2(HCl salt) enables the synthesis of molecules fortargeted protein degradation andPROTAC (proteolysis-targeting chimeras) technology. This conjugate contains a von Hippel–Lindau

DescriptionProtein degrader builiding block (S,R,S)-AHPC-PEG6-Alkyne enables the synthesis of molecules fortargeted protein degradation andPROTAC (proteolysis-targeting chimeras) technology. This conjugate contains a von Hippel-Lindau

DescriptionProtein degrader builiding block (S,R,S)-AHPC-PEG6-Azide enables the synthesis of molecules fortargeted protein degradation andPROTAC (proteolysis-targeting chimeras) technology. This conjugate contains a von Hippel–Lindau

DescriptionProtein degrader builiding block (S,R,S)-AHPC-PEG6-butyl amine (HCl salt) enables the synthesis of molecules fortargeted protein degradation andPROTAC (proteolysis-targeting chimeras) technology. This conjugate contains a von

DescriptionProtein degrader builiding block (S,R,S)-AHPC-PEG6-butyl azide enables the synthesis of molecules fortargeted protein degradation andPROTAC (proteolysis-targeting chimeras) technology. This conjugate contains a von Hippel–Lindau

DescriptionProtein degrader building block (S,R,S)-AHPC-PEG6-Butyl CO2H enables the synthesis of molecules fortargeted protein degradation andPROTAC (proteolysis-targeting chimeras) technology. This conjugate contains a von Hippel-Lindau

DescriptionProtein degrader builiding block (S,R,S)-AHPC-PEG6-NH2(HCl salt) enables the synthesis of molecules fortargeted protein degradation andPROTAC (proteolysis-targeting chimeras) technology. This conjugate contains a von Hippel-Lindau

Description(S,S,S)-AHPC (HCl salt) is a ligand used as a negative control for (S,R,S)-AHPC (cat#901490) in the recruitment of the von Hippel–Lindau (VHL) protein for targeted protein degradation and PROTAC (proteolysis-targeting chimeras) technology.

DescriptionSulfonyl fluoride motif can be used as a connector for the assembly of -SO2- linked small molecules with proteins or nucleic acids. This new click chemistry approach through sulfates is a complimentary approach to using amides and