General description

This certified reference material (CRM) is produced and certified in accordance with ISO/IEC 17025 and ISO 17034. This CRM is traceable to primary material from an NMI, e.g. NIST or NMIJ.
Certified content by quantitative NMR incl. uncertainty and expiry date are given on the certificate.
Download your certificate at: http://www.sigma-aldrich.com

Chlormequat chloride, also known as chlorocholine chloride (CCC) is the most widely used plant growth regulator that inhibits the biosynthesis of gibberellins. CCC is applied in agriculture and horticulture to promote sturdier growth by reducing the height of grain crops and increasing the diameter of the stems without causing a loss of plant productivity.

Chlormequat chloride has to be monitored in the Multiannual Control Programme for Pesticides Residues (MACP), run within the EU and EFTA in/on products of plant origin.
The European Communities (EC) have established maximum residue limits (MRLs) for CCC at 2 mg/kg for wheat, barley, and rye, 5 mg/kg for oat, and 0.05 mg/kg for other cereals. The agreed values of CCC as reported by EFSA are 0.04 mg/kg bw/day for the Acceptable Daily Intake (ADI), 0.04 mg/kg bw/day for the Acceptable Operator Exposure Level (AOEL), and 0.09 mg/kg bw/day for the Acute Reference Dose (ARfD).

According to Regulation (EU) No 540/2011, chlormequat is deemed to have been approved under Regulation (EC) No 1107/2009. This approval is restricted to its use as only a plant growth regulator.

Application

The certified reference material (CRM) is intended to be used as a calibrant for chromatography and other analytical techniques. Chlormequat chloride CRM may also find following uses:

Investigate the effect of drought on plant growth, essential oil concentration, oil biosynthesis, and peroxidase activity in the leaves of C. martinii and C. winterianus
Study the effect of ethrel, chlormequat chloride, and paclobutrazol on growth and pyrethrins levels in Chrysanthemum cinerariaefolium Vis.
Study the effect of chlormequat chloride (CCC) application at the bolting stage on the flowering, seed yield, and seed quality of lettuce plants previously treated with water or gibberellic acid (GA3)
Investigate the effects of nitrogen rate, seed rate, and chlormequat chloride on the grain quality of oats (Avena sativa)