General description
Chloroform, a halogenated hydrocarbon, is widely used as a solvent and extractant in various manufacturing and laboratory procedures. It can be produced by the chlorination of methane or lower-chlorinated methanes. Additionally, it is employed in the production of dichlorocarbenes, α-trichloromethyl carbinols, and trichlorolithiocarbenoids.
Application
Chloroform can be used as a solvent in the:
- Enzyme-catalyzed ring-opening polymerization of ω-pentadecalactone to prepare polyesters.
- Pd-catalyzed cross-coupling reaction of acid chlorides with arylboronic acids to synthesize diaryl Ketones.
- Enantio- and diastereoselective nitro-Mannich reaction of α-aryl nitromethanes with amido sulfones to synthesize β-nitroamines.
- Diels-Alder reaction to synthesize spiro-fused dihydropyans. The hydrogen bond (CH-O) formed between chloroform and carbonyl oxygen makes the carbonyl group a stronger heterodienophile, resulting in an increased reaction rate.
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- UPC:
- 51272501
- Condition:
- New
- Availability:
- 3-5 Days
- Weight:
- 1.00 Ounces
- HazmatClass:
- Yes
- MPN:
- 319988-500ML
- CAS:
- 67-66-3
- Temperature Control Device:
- Yes
