Muscarinic acetylcholine receptors belong to a superfamily of seven-™-domain receptors that interact with G-proteins to initiate intracellular responses. Five muscarinic receptor subtypes have been identified and named from M1 to M5. The M2 muscarinic receptor couples to Gi/o to inhibit cAMP production. GenScript co-transfected human M2 with Ga15 in the CHO-K1 which supports high levels of recombinant M2 expression on the cell surface and contains high levels of Ga15 to couple the receptor to the calcium signaling pathway.
- UPC:
- 41122409
- Condition:
- New
- Availability:
- 3 Days
- Weight:
- 1.00 Ounces
- HazmatClass:
- No
- WeightUOM:
- LB
- MPN:
- M00258
