General description
Cholecalciferol (vitamin D3), a fat-soluble steroid is produced in the skin.
Application
Cholecalciferol has been used:
- to induce arterial medial calcification (AMC) in mice
- to study its impact in vascular remodeling associated with vascular calcification (VC) in murine model of obesity and insulin resistance (ob/ob mice)
- to study its effect on anchorage dependent growth of RWPE2-W99 cells in monolayer culture
Biochem/physiol Actions
Vitamin D acts through a receptor that is a member of the ligand-dependent transcription factor superfamily. Modulates the proliferation and differentiation of both normal and cancer cells. Has antiproliferative and antimetastatic effects on breast, colon, and prostate cancer cells. Activated vitamin D receptors in intestine and bone maintain calcium absorbance and homeostasis.
Shipping Information:
Hazmat Fee: $65.00 + applicable shipping charges are added after the order is placed.
More Information: https://cenmed.com/shipping-returns
- UPC:
- 51171522
- Condition:
- New
- Availability:
- 3-5 Days
- Weight:
- 1.00 Ounces
- HazmatClass:
- Yes
- MPN:
- C1357-1G
- CAS:
- 67-97-0
