Chromatography

A blood brain barrier permeable, positive allosteric modulator of the metabotropic GABA B receptor. Shown to modulate GABA B receptor in the high affinity state and thereby increases agonist affinity for the receptor.

Biochem/physiol Actions Positive allosteric modulator of GABA B receptors. Features and Benefits This compound is a featured product for Neuroscience research.

Application CGP-20712A methanesulfonate salt has been used as a &#9461-adrenergic receptor antagonist in adult rat ventricular myocytes (ARVM) and rat cardiac fibroblasts. It may also be used as an antagonist for the &#9461-adrenergic receptor in

CGP-37157 is a benzothiazepine compound, which is derived from clonazepam. It functions as a sarco/endoplasmic reticulum Ca 2+ ATPase (SERCA) antagonist and ryanodine receptor channels (RyR) agonist.

CGP-37157 is a benzothiazepine compound, which is derived from clonazepam. It functions as a sarco/endoplasmic reticulum Ca 2+ ATPase (SERCA) antagonist and ryanodine receptor channels (RyR) agonist.

A cell-permeable benzothiazepine derivative of clonazepam that acts as a specific and potent inhibitor of the mitochondrial Na + /Ca 2+ exchanger (IC 50 = 360 nM). Enhances the export of Ca 2+ from isolated mitochondria.

Amino Acid Sequence Tyr-Z-Arg-Lys-His-Pro-Ile Application CGP-42112A has been used: in the isolation of RNA from fibroblast-like synoviocytes from rheumatoid arthritis patients (RA-FLS) to study its effects on the ERK2 phosphorylation in the

Amino Acid Sequence Tyr-Z-Arg-Lys-His-Pro-Ile Application CGP-42112A has been used: in the isolation of RNA from fibroblast-like synoviocytes from rheumatoid arthritis patients (RA-FLS) to study its effects on the ERK2 phosphorylation in the

CGP-53716.

CGP-53716.

CGP-53716.

Application CGS-15943 has been used as a non-selective adenosine receptor antagonist to study its effects on the proliferation of pancreatic ductal adenocarcinoma (PDAC) cells and hepatocellular carcinoma (HCC) . It has also been used as a