General description
A potent thiazolinedione (TDZ) type anti-hyperglycemic agent and a selective PPARγ agonist (EC50 = 3 µM).
A potent thiazolinedione (TDZ) type anti-hyperglycemic agent and a selective peroxisome proliferator-activated receptor γ (PPARγ) agonist (EC50 = 3 µM).
Biochem/physiol Actions
Cell permeable: no
EC50 = 3 µM as PPARγ agonist
Primary Target
Selective PPARγ agonist
Product does not compete with ATP.
Reversible: no
Warning
Toxicity: Harmful (C)
Reconstitution
Stock solutions are stable for up to 3 months at -20°C.
Other Notes
Jha, R.J. 1999. Clin. Exp. Hypertens. 21, 157.
Xin, X., et al. 1999. J. Biol. Chem. 274, 9116.
Lohrke, B., et al. 1998. J. Endocrinol. 159, 429.
Willson, T.M., et al. 1996. J. Med. Chem. 39, 665.
Cantello, B.C., et al. 1994. J. Med. Chem. 37, 3977.
Legal Information
CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany
- UPC:
- 51412004
- Condition:
- New
- Weight:
- 1.00 Ounces
- HazmatClass:
- No
- WeightUOM:
- LB
- MPN:
- 230950-5MG