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cilnidipine (c15-1211-902)

Cilnidipine (C15-1211-902)

Catalog No.
C15-1211-902
Manufacturer No.
C1493-50MG
Manufacturer Name
Sigma-Aldrich
Quantity
50
Unit of Measure
MG
Price: $1,188.00
List Price: $1,320.00

Application Cilnidipine has been used: in cell viability assay of pheochromocytoma (nPC12) cells in photoirradiation and photodegradation studies to understand effect on albuminuria in diabetic nephropathy Biochem/physiol Actions Cilnidipine is a

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Application

Cilnidipine has been used:

  • in cell viability assay of pheochromocytoma (nPC12) cells
  • in photoirradiation and photodegradation studies
  • to understand effect on albuminuria in diabetic nephropathy

Biochem/physiol Actions

Cilnidipine is a slow-acting Ca2+ channel blocker; antihypertensive; vasodilator; dual blocker of L-type voltage-gated Ca2+ channels in vascular smooth muscle and N-type Ca2+ channels in sympathetic nerve terminals that supply blood vessels. Cilnidipine may offer an advantage over nifedipine as the long term intake of the latter has been linked to increased risk of myocardial infarction and mortality in patients with coronary artery disease. Cilnidipine lowers blood pressure, but has less effect on sympathetic activity. Unlike nifedipine, cilnidipine does not inhibit PKC.

Features and Benefits

This compound is featured on the Calcium Channels page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

Packaging

Protect from high temperatures.

UPC:
51433912
Condition:
New
Weight:
1.00 Ounces
HazmatClass:
No
WeightUOM:
LB
MPN:
C1493-50MG


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