General description
Reversible active-site inhibitor of lysosomal α-mannosidase. Inhibits the growth of tumors and prevents metastasis in murine models. Blocks the processing of high mannose to complex type oligosaccharides.
Biochem/physiol Actions
Primary Target
Lysosomal α-mannosidase
Warning
Toxicity: Harmful (C)
Reconstitution
Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 1 month at -20°C.
Other Notes
Mochizuki, H., et al. 1993. J. Biol. Chem. 268, 9143.
Elbein, A.D. 1983. Methods Enzymol.98, 135.
Legal Information
CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany
- UPC:
- 51191509
- Condition:
- New
- Availability:
- 3-5 Days
- Weight:
- 1.00 Ounces
- HazmatClass:
- No
- MPN:
- 574775-500UG
- CAS:
- 72741-87-8