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citraconic anhydride 10g un2810

CITRACONIC ANHYDRIDE 10G UN2810

Catalog No.
C08-0403-061
Manufacturer No.
786-389
Manufacturer Name
GENO TECHNOLOGY INC.
Quantity
1
Unit of Measure
EA
Price: $65.07
List Price: $72.30
*Additional Hazmat Fee will apply

Citraconic anhydride reacts with primary amines and blocks them by creating an amide linkage and a terminal carboxylate. The linkage is stable at neutral to alkaline pH (pH >7) and at acidic conditions (pH 4) the amide linkage is rapidly

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Citraconic anhydride reacts with primary amines and blocks them by creating an amide linkage and a terminal carboxylate. The linkage is stable at neutral to alkaline pH (pH >7) and at acidic conditions (pH 4) the amide linkage is rapidly hydrolyzed to release the citraconic acid and free the amines.The block by citraconic anhydride can also be reveresed by treatment with hydroxylamine .This property makes citraconic anhydride a very useful tool for blocking free amines in proteins and other biomolecules. Features Reversible blocking of primary amines Reactive towards primary amines Synonym: 2-methylmaleic anhydride Empirical formula:C5H4O3 CAS # 616-02-4 Molecular weight: 112.08 Form: Colorless to slight yellow, clear liquid Applications Temporarily block amines to allow derivatization of other parts of the molecule. Block removed by shifting to acidic conditions (pH3-4) or treatment with hydroxylamine
UPC:
12350000
Condition:
New
Availability:
3 Days
Weight:
1.00 Ounces
HazMatClass:
Yes
WeightUOM:
LB
MPN:
786-389
CAS:
616-02-4


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