A highly sensitive, rhodamine phenylglyoxal-based fluorophore that specifically detects protein citrullination via a chemoselective reaction between glyoxal and citrulline; reacts with any citrulline-containing protein and can be analyzed with fluorescent imaging (Ex. 532 nm; Em. 580 nm); limit of detection of ~10 ng for citrullinated histone H3 and ~1 ng for autodeiminated PAD4 when applied at 100 µM for 30 minutes at acidic pH.
- UPC:
- 12350000
- Condition:
- New
- Availability:
- 3 Days
- Weight:
- 1.00 Ounces
- HazmatClass:
- No
- WeightUOM:
- LB
- MPN:
- 16172-500
