Colchicine, a tubulin Inhibitor, has been shown to block polymerization of microtubules by binding to tubulin. Studies indicate that this reagent also causes apoptosis of cells by acting on tissue plasminogen activators (tPA) and disrupting the cytoskeleton of cells. Exposure of cells to Colchicine has also been reported to result in alterations of Ca2+ concentrations in cells which may also result in apoptosis.A mitosis inhibitor useful in cell division studies. Specifications and Purity: for plant cell culture,≥98%(HPLC). MDL Number: MFCD00078484. Molecular Formula: C22H25NO6. Molecular Weight: 399.44. EC Number: 200-598-5. PubChem CID: 6167. Isomeric SMILES: CC(=O)N[C@H]1CCC2=CC(=C(C(=C2C3=CC=C(C(=O)C=C13)OC)OC)OC)OC. Beilstein Registry Number: 2228813. Related Document: https://ald-pub-files.oss-cn-shanghai.aliyuncs.com/aladdinsci/pdp/sds/1/C106740-SCI_f4310337b8348cfc0cf10fc08d854839.pdf.
- UPC:
- 12352210
- Condition:
- New
- Availability:
- 2 weeks
- Weight:
- 1.05 Ounces
- HazmatClass:
- No
- WeightUOM:
- LB
- MPN:
- C106740-1g
- CAS:
- 64-86-8
- Health Hazards:
- Toxic
- Product Size:
- 1g
- Hazard Statement Codes:
- H300:H340
- Precautionary Statement Codes:
- P201:P264:P301+P310:P308+P313
