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colistin sulfate salt (c15-1209-913)

Colistin sulfate salt (C15-1209-913)

Catalog No.
C15-1209-913
Manufacturer No.
C4461-100MG
Manufacturer Name
Sigma-Aldrich
Quantity
100
Unit of Measure
MG
Price: $129.04
List Price: $143.38

Chemical structure: peptide Application Colistin sulfate is used to permeabilize bacterial cell membranes and to study mannose-resistant haemagglutination and antibiotic resistance in certain organisms such as A. baumannii .

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General description

Chemical structure: peptide

Application

Colistin sulfate is used to permeabilize bacterial cell membranes and to study mannose-resistant haemagglutination and antibiotic resistance in certain organisms such as A. baumannii . It has been used to study hephrotoxicity in the rat kidney , and MICs, time-kill kinetics, and postantibiotic effect (PAE) against Pseudomonas aeruginosa .

Biochem/physiol Actions

Mode of Action: Binds to lipids on the cell cytoplasmic membrane of Gram-negative bacteria and disrupts the cell wall integrity.
Antimicrobial spectrum: Gram-negative bacteria.

Mode of Action: Binds to lipids on the cell cytoplasmic membrane of Gram-negative bacteria and disrupts the cell wall integrity.
Antimicrobial spectrum: Gram-negative bacteria. It is proposed that renal reabsorption of colistin may involve organic cation transporters and peptide transporters and that the process is sensitive to pH .

Analysis Note

Freely soluble in water, practically insoluble in acetone and in ethanol (96%)

Other Notes

Keep container tightly closed in a dry and well-ventilated place.

UPC:
51284506
Condition:
New
Weight:
1.00 Ounces
HazmatClass:
No
WeightUOM:
LB
MPN:
C4461-100MG


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