General description

Enhances luminescent signals and have low background luminescence and fluorescence
Designed to reduce well-to-well crosstalk
Nonbinding (NBS^™) surface is a Corning proprietary treatment technology used on polystyrene microplates to create a nonionic hydrophilic surface (polyethylene oxide-like) that minimizes molecular interactions
Ideal for reducing protein and nucleic acid binding at low concentrations, and increasing assay signal to noise
Can be used for both top and bottom reading instruments
Without lids, lids supplied separately
Recommended working volume of 75 to 200 μL
Conforms to standard microplate footprint and dimensions

Non-Binding surface (NBS) multiwell plates have a modified polymer surface (PS) which results in a non-ionic hydrophilic surface (polyethylene oxide-like), thereby minimizing bio-interaction and enhancing the signal-to-noise ratio. Results have demonstrated NBS′s ability to significantly reduce protein and nucleic acid binding to polymers (<2 ng/cm²; over 90% reduction of protein binding compare to PS & PP surface), maintain enzyme activity, and inhibit adhesion of a number of cell lines. These novel surface technologies for assay plates are ideal for homogeneous assays such as Scintillation Proximity Assay (SPA). In addition to a 20+ fold increase in signal-to-noise ratio, selected assays have also displayed improved sensitivity and specificity. The recommended working volume of up to 75 μL to 200 μL for 96 well plates and 20μL to 80 μL for 384 well plates.