Application
Cortisone has been used:
- to validate a 1β-HSD1 (11β-hydroxysteroid dehydrogenase type 1) inhibitor
- to study the sensitivity of erythropoietic and granulopoietic progenitor cells to cortisone
- in the determination of rates of cortisol oxidation by 11βHSD
Biochem/physiol Actions
Cortisone (11 dehydro 17 hydroxycortico-sterone) is an anti-inflammatory glucocorticoid that delays wound healing after surgeries. It postpones the healing process by affecting the appearance of inflammatory cells, ground substance, fibroblasts, collagen, regenerating capillaries, and epithelial migration. Glucocorticoids have anti-inflammatory, anti-allergic and immunosuppressive properties and are extensively used in treatment and therapy.
Cortisone is a glucocorticoid; a corticosterone analog that has approximately twice the anti-inflammatory potency as corticosterone but much lower Na2+ retention potency.
Packaging
Bottomless glass bottle. Contents are inside inserted fused cone.
- UPC:
- 51422401
- Condition:
- New
- Availability:
- 3-5 Days
- Weight:
- 1.00 Ounces
- HazmatClass:
- No
- MPN:
- C2755-250MG
- CAS:
- 53-06-5
