CP 24,879 (hydrochloride) (C09-0818-452)

Essential fatty acid deficiency symptoms include immune system depression and a general state of inflammatory inhibition. CP 24,879 is an inhibitor of arachidonic acid biosynthesis acting via the inhibition of Δ5/Δ6 desaturase. Mice injected with CP 24,879 at 3 mg/kg had a reduction of liver arachidonate content of approximately 50%. Murine mastocytoma cells treated with 5 μM CP 24,879 showed increased mead acid content and nearly complete ablation of leukotriene C4 synthesis, consistent with a desaturase inhibition-induced state of essential fatty acid deficiency. Specification: 0.98 Molecular Formula: C11H18NOCl Molecular Weight: 215.72 PubChem CID: 16078965 Isomeric SMILES: CC(C)CCOC1=CC=C(C=C1)N.Cl Related Documents: https://ald-pub-files.oss-cn-shanghai.aliyuncs.com/aladdinsci/pdp/sds/1/C338229-SCI_b84e9217a905d822d8d15e77b6121acc.pdf