Interleukin-2-inducible T-cell kinase (ITK) inhibitor (IC50 values are 0.1, 0.4 and 5 μM for ITK, BTK and ETK, respectively). Inhibits growth of cancer cells expressing ITK, including MOLT-4 and Jurkat cells in vitro. Induces apoptosis in Jurkat cells. Inhibits MOLT-4 xenograft tumor growth in mice.Application：CTA 056 is an ITK (IL-2 induced T cell kinase) inhibitor with an IC50 of 0.1 μM. CTA 056 selectively targets malignant T cells and regulates tumor cells. CTA 056 induces apoptosis and is a potential therapeutic agent for the treatment of T-cell leukemia and lymphoma. Specifications and Purity: ≥98%(HPLC). Molecular Formula: C35H34N6O. Molecular Weight: 554.68. PubChem CID: 49870925. Isomeric SMILES: C1CCN(CC1)CCCN2C3=C(C=C4C(=C3)N=C(C(=O)N4)CC5=CC=CC=C5)N=C2C6=CC=C(C=C6)C7=CC=NC=C7. Related Document: https://ald-pub-files.oss-cn-shanghai.aliyuncs.com/aladdinsci/pdp/sds/1/C288366-SCI_1ba4644c1fee02d9a04beab99c6506e1.pdf.
- UPC:
- 12352005
- Condition:
- New
- Availability:
- 8-12 weeks
- Weight:
- 0.96 Ounces
- HazmatClass:
- No
- WeightUOM:
- LB
- MPN:
- C288366-2mg
- CAS:
- 1265822-30-7
- Product Size:
- 2mg
