Curcumin (C09-0825-516)

DescriptionCurcumin is a yellow-colored polyphenol obtained from the rhizome ofCurcuma longaL. It constitutes an important part of various diets and herbal medicines, especially in the Asian continent for its various salubrious effects on human health.Curcumin has been used:to study its effect on the consequences and mechanism involved in the suppression of human homeobox gene NKX3.1 in the prostate cancer cell LNCaPto examine its effect on stress in pigs by having an inhibitory impact on the serum cortisol concentration, hippocampal nitric oxide production, and brain-derived neurotrophic factor expressionto study its effect as a dietary supplement on the growth, immunity, antioxidant activity, and disease resistance inOreochromis niloticusto analyze its protective effect on the organotypic hippocampal slice cultures against the synaptic toxicity caused by amyloid beta peptides (Aβ1–42)to examine the possibility of its non-toxic concentrations to decrease the inflammation caused by interleukin-1beta (IL-1β) in cartilage explant culturesto study its protective impact against intestinal ischemia-reperfusion injury in ratsto measure its antibacterial activityin vitroto determine its preventative effects for Alzheimer′s disease (AD) in miceas a bifunctional agent for generation and validation of the erythroid 2-related factor 2 (Nrf2) reporter systemto study itsin vitroinhibitory effects on human liver glucuronidation activityto evaluate its effects on Parkinson′s disease (PD)-like phenotypes. Specifications and Purity: from Curcuma longa (Turmeric), powder. MDL Number: MFCD00008365. Molecular Formula: C21H20O6. Molecular Weight: 368.38. EC Number: 207-280-5. PubChem CID: 969516. Isomeric SMILES: COC1=C(C=CC(=C1)/C=C/C(=O)CC(=O)/C=C/C2=CC(=C(C=C2)O)OC)O. Beilstein Registry Number: 2306965. Related Document: https://ald-pub-files.oss-cn-shanghai.aliyuncs.com/aladdinsci/pdp/sds/1/C477437-SCI_f933d524e3e05f78c634fc34a9436ee7.pdf.