![cyclo(7-aminoheptanoyl-phe-d-trp-lys-thr[bzl])](https://cdn11.bigcommerce.com/s-2u2oi3cvy8/images/stencil/1280x1280/products/908670/736599/cenmed-product-image-placeholder-1-__21906.1717466080.jpg?c=1 "cyclo(7-aminoheptanoyl-phe-d-trp-lys-thr[bzl])")
Amino Acid Sequence
cyclo-Phe-Trp-Lys-Thr-Bzl
Application
Cyclo(7-aminoheptanoyl-Phe-D-Trp-Lys-Thr[Bzl]) has been used as a somatostatin antagonist to study its effects on sleep in rats to infer the role of endogenous somatostatin in the physiologic modulation of REM sleep (REMS) , as an somatostatin (SST) antagonist to study its effects on elemental-induced intestinal atrophy in rats , as an SST receptor antagonist to eliminate the effect of somatostatin on catecholamine .
Biochem/physiol Actions
Cyclo(7-aminoheptanoyl-Phe-D-Trp-Lys-Thr[Bzl]) (cSSTA) is a cyclic somatostatin (SST) analog and is a somatostatin receptor antagonist. It is involved in blocking the effect of somatostatin, such as airway β-adrenergic function and regulation of acetylcholine release. cSSTA is also involved in blocking the effect of somatostatin of hormone release and corticotropin-releasing factor-induced suppression of gastric emptying.
Cyclo(7-aminoheptanoyl-Phe-D-Trp-Lys-Thr[Bzl]), also known as cyclosomatostatin. Inhibition of somatostatin receptors by cyclosomatostatin induces catalepsy in rats.
- UPC:
- 51432700
- Condition:
- New
- Weight:
- 1.00 Ounces
- HazmatClass:
- No
- WeightUOM:
- LB
- MPN:
- C4801-1MG
![h-c[cys-phe-lagl(nβme,benzoyl)-trp-lys-thr-phe-cys]-oh (c09-1188-005)](https://cdn11.bigcommerce.com/s-2u2oi3cvy8/images/stencil/500x659/products/1595677/1426932/db_700_rp174198__78201.1721214780.jpg?c=1 "h-c[cys-phe-lagl(nβme,benzoyl)-trp-lys-thr-phe-cys]-oh (c09-1188-005)")
