Application
Cyclophosphamide, a nitrogen mustard DNA alkylating agent, is used to study its mechanisms of action as an anticancer and antiimmunity drug.
Biochem/physiol Actions
Cyclophosphamide is a cytotoxic nitrogen mustard derivative widely used in cancer chemotherapy. It cross-links DNA, causes strand breakage, and induces mutations. Its clinical activity is associated with a decrease in aldehyde dehydrogenase 1 (ALDH1) activity.
Packaging
Packaged in a 100 mL serum bottle with silicon/PTFE septum and aluminum tear seal.
Caution
Injecting a compatible solvent directly into the vial permits preparation of any desired strength solution without exposure.
Reconstitution
Dissolving the contents in 100 mL of solvent yields a 1% solution.
Legal Information
Isopac is a registered trademark of Sigma-Aldrich Co. LLC
- UPC:
- 51112202
- Condition:
- New
- Weight:
- 1.00 Ounces
- HazmatClass:
- No
- WeightUOM:
- LB
- MPN:
- C7397-1G