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Cyclopiazonic acid from Penicillium cyclopium (C15-1220-476)

Sigma-Aldrich

Catalog No.
C15-1220-476
Manufacturer No.
C1530-5MG
Manufacturer Name
Sigma-Aldrich
Quantity
5
Unit of Measure
MG
Price: $252.86
List Price: $280.95

Cyclopiazonic acid (CPA), a tetramic acid is synthesized by various Aspergillus and Penicillium species. Application Cyclopiazonic acid from  Penicillium cyclopium has been used: as a standard in aflatoxin detection and quantification by thin

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General description

Cyclopiazonic acid (CPA), a tetramic acid is synthesized by various Aspergillus and Penicillium species.

Application

Cyclopiazonic acid from Penicillium cyclopium has been used:

  • as a standard in aflatoxin detection and quantification by thin layer chromatography (TLC)
  • as a component in Ca2+-free DMEM/10% fetal bovine serum (FBS)
  • as a reversible inhibitor of the sarco/endoplasmic reticulum Ca2+-ATPase (SERCA) to examine the role of luminal calcium in endoplasmic recticulum (ER)-to-Golgi trafficking
  • as an endoplasmic reticulum Ca2+-ATPase blocker, to treat neurons and also to study the role of the endoplasmic reticulum (ER) in releasing and sustaining Ca2+ during Ca2+-induced Ca2+ release (CICR) to inhibit SERCA

Biochem/physiol Actions

Inhibits the sarcoplasmic reticulum Ca2+-pump.

UPC:
51284705
Condition:
New
Weight:
1.00 Ounces
HazmatClass:
No
WeightUOM:
LB
MPN:
C1530-5MG


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