General description
Supplied as purified soluble proteins, rather than microsomal preparations.
Application
Cytochrome P450 3A4 human has been used in circular dichroism analysis.
Biochem/physiol Actions
Cytochrome P450 3A4 (CYP3A4) is one of the isoform of cytochrome P450 (P450s). Cytochrome P450s (P450s) play a vital role in processing endogenous compounds and xenobiotics, including pollutants, environmental compounds and drug molecules. CYP3A4 oxidizes more than 90% of marketed drugs through various metabolic processes.
Unit Definition
One unit will convert 1.0 nanomole of testosterone to 6-beta-testosterone per minute at pH 7.4 at 37 °C.
Other Notes
Visit our drug metabolism resources: www.sigmaaldrich.com/life-science/metabolomics/enzyme-explorer/cell-signaling-enzymes/xenobiotics.html
Shipping Information:
Dry Ice Surcharge & Ice Pack Shipments: $40
More Information: https://cenmed.com/shipping-returns
- UPC:
- 51182056
- Condition:
- New
- Availability:
- 3-5 Days
- Weight:
- 1.00 Ounces
- HazmatClass:
- No
- MPN:
- H5042-1000PMO
- CAS:
- 9035-51-2
- Temperature Control Device:
- Yes
