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[d-arg1, d-phe5, d-trp7,9, leu11]-substance p

(D-ARG1 D-PHE5 D-TRP7 9 LEU11)- SUBSTANCE P

Catalog No.
C005B-371069
Mfr. No.
S3144-1MG
Mfr. Name
Sigma-Aldrich
Qty/UOM
1
UOM
MG
Price: $431.51
List Price: $479.45

Amino Acid Sequence Arg-Pro-Lys-Pro-Phe-Gln-Trp-Phe-Trp-Leu-Leu-NH2 General description The somatostatin gene codes for a peptide hormone containing 14 and 28 amino acid moieties. SST-14 is highly expressed in the central nervous system and

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Amino Acid Sequence

Arg-Pro-Lys-Pro-Phe-Gln-Trp-Phe-Trp-Leu-Leu-NH2

General description

The somatostatin gene codes for a peptide hormone containing 14 and 28 amino acid moieties. SST-14 is highly expressed in the central nervous system and peripheral organs. SST-28 is mainly expressed in enteroendocrine cells of the intestine.

Biochem/physiol Actions

Somatostatin plays an important role in regulating the metabolism of other hormones such as growth hormone, insulin, IGF-1 (insulin-like growth factor 1), glucagon, glucagon-like peptide and gastrin. Somatostatin has both regulatory and inhibitory functions. It retards gastrointestinal motility and gallbladder contraction, suppresses gut exocrine secretion and reduces epithelial proliferation. Somatostatin is associated with intestinal nutrient absorption and blood flow regulation. This peptide hormone is believed to inhibit cell proliferation and promote apoptosis. Somatostatin acts as a neurotransmitter and neuromodulator, and is also associated in maintaining water balance.

NK-1 tachykinin receptor antagonist

UPC:
51171644
Condition:
New
Availability:
3-5 Days
Weight:
1.00 Ounces
HazmatClass:
No
MPN:
S3144-1MG
CAS:
96736-12-8

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