D-myo-Inositol-1,3,4-triphosphate sodium salt is one of many inositol oligophosphate isomers implicated in signal transduction. Ins(1,3,4)-P3 acts through the inhibition of Ins(3,4,5,6)-P4 kinase activity to increase the cellular level of Ins(3,4,5,6)-P4 and thus inhibit calcium-activated chloride channels. The levels of Ins(1,3,4)-P3 are regulated by the levels of cytosolic free calcium. The receptor-mediated activation of phospholipase C (PLC) can be seen as the initiating event in this cascade, since PLC generates Ins(1,4,5)-P3 which releases calcium from intracellular storage reservoirs. This leads to increase in the cytosolic concentration of free calcium.D-myo-Inositol-1,3,4-triphosphate sodium saltis an inhibitor of Ins(3,4,5,6)-P4 kinase activity. Specifications and Purity: ＞98%. Molecular Formula: C6H12O15P3•3Na. Molecular Weight: 486.04. PubChem CID: 53394553. Isomeric SMILES: C1(C(C(C(C(C1OP(=O)(O)[O-])O)OP(=O)(O)[O-])O)OP(=O)(O)[O-])O.[Na+].[Na+].[Na+]. Related Document: https://ald-pub-files.oss-cn-shanghai.aliyuncs.com/aladdinsci/pdp/sds/1/D378581-SCI_72127dda0b17a9af1e9c2513914fe152.pdf.
- UPC:
- 12141806
- Condition:
- New
- Availability:
- 8-12 weeks
- Weight:
- 0.96 Ounces
- HazmatClass:
- No
- WeightUOM:
- LB
- MPN:
- D378581-500μg
- Product Size:
- 500μg
- Precautionary Statement Codes:
- P264
