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Daidzein - CAS 486-66-8 - Calbiochem

Catalog No.
C15-1243-241
Manufacturer No.
251600-25MG
Manufacturer Name
Sigma-Aldrich
Quantity
25
Unit of Measure
MG
Price: $182.57
List Price: $202.86

Inactive analog of Genistein (Cat. No.

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General description

Inactive analog of Genistein (Cat. No. 345834). Blocks the G1 phase of the cell cycle in Swiss/3T3 cells by inhibiting casein kinase II activity. Inhibits the growth of MiaPaC-2 and PANC-1 cells (IC50= 45 µM and 75 µM, respectively).

Inactive analog of genistein (Cat. No. 345834). Blocks the G1 phase of the cell cycle in Swiss 3T3 cells by inhibiting casein kinase II activity. Inhibits epidermal growth factor (EGF) receptor autophosphorylation (IC50 >300 µM). Inhibits the growth of MiaPaC-2 and PANC-1 cells (IC50= 45 µM and 75 µM, respectively).

Biochem/physiol Actions

Cell permeable: no

Primary Target
MiaPaC-2, PANC-1

Product does not compete with ATP.

Reversible: no

Target IC50: 45 µM, 75 µM for inhibiting the growth of MiaPaC-2 and PANC-1 cells, respectively

Packaging

Packaged under inert gas

Warning

Toxicity: Irritant (B)

Reconstitution

Following reconstitution, aliquot and freeze (-20°C) under an inert gas. DMSO stock solutions are stable for up to 2 months at -20°C.

Other Notes

Guo, J-M., et al. 2004. World J. Gastroenterol.10, 860.
Higashi, K., and Ogawara, H. 1994. Biochim. Biophys. Acta 1221, 29.
Lavens, S.E., et al. 1992. Am. J. Respir. Cell Mol. Biol.7, 637.
Akiyama, T., et al. 1987. J. Biol. Chem.262, 5592.

Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

UPC:
51281665
Condition:
New
Weight:
1.00 Ounces
HazmatClass:
No
WeightUOM:
LB
MPN:
251600-25MG


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