Dalotuzumab (anti-IGF1R) is a recombinant humanized monoclonal antibody (IgG1 type) targeting IGF-1R. Dalotuzumab (anti-IGF1R) acts by inhibiting IGF-1- and IGF-2-mediated tumor cell proliferation, IGF-1R autophosphorylation, and Akt phosphorylation. Dalotuzumab (anti-IGF1R) also induces apoptosis and cycle arrest. Dalotuzumab (anti-IGF1R) in combination with other anticancer agents such as statins can enhance the antitumor activity of Dalotuzumab (anti-IGF1R) in vitro and in vivo.
Specification: ExactAb™, Validated, Carrier Free, Low Endotoxin, Azide Free, Recombinant, ≥95%(SDS-PAGE&SEC), Lot by Lot
Molecular Weight: 146.4 (kDa)
Related Documents: https://ald-pub-files.oss-cn-shanghai.aliyuncs.com/aladdinsci/pdp/sds/1/AB183419-SCI_b2ffba15aab9f49105aab6484fc2be66.pdf
- UPC:
- 51202411
- Condition:
- New
- Availability:
- 4-8 weeks
- Weight:
- 0.07 Ounces
- HazmatClass:
- No
- WeightUOM:
- LB
- MPN:
- Ab183419-10mg
- CAS:
- 1005389-60-5
- Product Size:
- 10mg