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dalpiciclib hydrochloride (c09-1126-805)

Dalpiciclib hydrochloride (C09-1126-805)

Aladdin

Catalog No.
C09-1126-805
Manufacturer No.
D659080-25mg
Manufacturer Name
Aladdin Scientific
Quantity
1
Unit of Measure
EA
Price: $1,685.65
List Price: $1,872.95

Dalpiciclib (SHR-6390) hydrochloride is an orally active and highly selective inhibitor of CDK4 and 6 with IC 50 values of 12.4 nM and 9.9 nM, respectively. Dalpiciclib hydrochloride shows antitumor activity against breast cancer and esophageal

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Dalpiciclib (SHR-6390) hydrochloride is an orally active and highly selective inhibitor of CDK4 and 6 with IC 50 values of 12.4 nM and 9.9 nM, respectively. Dalpiciclib hydrochloride shows antitumor activity against breast cancer and esophageal sAppearance:SolidIC50& Target:CDK6 9.9 nM (IC 50 ) CDK4 12.4 nM (IC 50 )In Vitro:Dalpiciclib hydrochloride (0-4 μM, 72 h) inhibits cell proliferation in a dose-dependent manner. Dalpiciclib hydrochloride (0-10 μM, 6 d) inhibits the proliferation of retinoblastoma-positive tumor cell lines. MCE has not independently confirmedIn Vivo:Dalpiciclib hydrochloride (oral gavage; 150mg/kg; once weekly; 3 weeks) shows antitumor activity against ESCC xenografts. Dalpiciclib hydrochloride combined with Paclitaxel (PTX) or Cisplatin (CDDP) offer synergistic inhibitory effects in ESCC xenogBiological Activity:Dalpiciclib (SHR-6390) hydrochloride is an orally active and highly selective inhibitor of CDK4 and 6 with IC 50 values of 12.4u2009nM and 9.9u2009nM, respectively . Dalpiciclib hydrochloride shows antitumor activity against breast cancer and esop. Specification: 0.99 Molecular Formula: C25H31ClN6O2 Molecular Weight: 483.01
UPC:
12352107
Condition:
New
Availability:
8-12 weeks
Weight:
1.09 Ounces
HazmatClass:
No
WeightUOM:
LB
MPN:
D659080-25mg
Product Size:
25mg


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