General description
Activator solution, containing powerful activators like 4,5-dicyanoimidazole(DCI), 5-(3,5-bis(trifluoromethyl)phenyl)-1H-tetrazole (Activator 42) or5-(Ethylthio)-1H-tetrazole (ETT) in acetonitrile, are mixed with solutions ofphosphoramidites during the extension step. The activator reacts with theamidite group to form a highly reactive intermediate. The intermediate thenforms an internucleotide bond with the detritylated 5′hydroxyl group of thegrowing oligonucleotide chain.
Preparation Note
Dicyanoimidazole / Acetonitrile 3/100 (w/v)
Quality Level: 200. type: for DNA synthesis, for DNA synthesis. product line: Proligo Reagents. storage condition: dry at room temperature. concentration: 29-32 . g/L (DCI content, titration). impurities: ≤. 30 . ppm water content (Karl Fischer), ≤. 30 . ppm water content (Karl Fischer). color: clear, clear. Pictograms: GHS02,GHS05,GHS07. Signal Word: Danger. Hazard Statements: H225 - H302 + H312 + H332 - H315 - H318 - H335. Precautionary Statements: P210 - P280 - P301 + P312 - P303 + P361 + P353 - P304 + P340 + P312 - P305 + P351 + P338. Hazard Classifications: Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Eye Dam. 1 - Flam. Liq. 2 - Skin Irrit. 2 - STOT SE 3. Target Organs: Respiratory system. Storage Class Code: 3 - Flammable liquids. WGK: WGK 3. Flash Point(F): 41.0 °F. Flash Point(C): 5 °C.- UPC:
- 41113700
- Condition:
- New
- Weight:
- 1.00 Ounces
- HazmatClass:
- No
- WeightUOM:
- LB
- MPN:
- L032000-4X2.5L
