Deoxynivalenol (C15-1245-394)

Catalog No.: C15-1245-394
Manufacturer No.: D0156-5MG
Manufacturer Name: Sigma-Aldrich
Quantity: 5
Unit of Measure: MG

Price: $673.71

List Price: $748.57

Deoxynivalenol (DON) is a natural mycotoxin found in Fusarium graminearum and Fusarium culmorum . It belongs to the B-trichothecenes family of mycotoxins.

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Description
Specifications

General description

Deoxynivalenol (DON) is a natural mycotoxin found in Fusarium graminearum and Fusarium culmorum. It belongs to the B-trichothecenes family of mycotoxins.

Application

Deoxynivalenol has been used:

as a mycotoxin to induce cytotoxicity in porcine jejunal epithelial cells and study the protective effects of Saccharomyces cerevisiae on the cell viability of host cells.
to induce toxicity in nude mice to study the effect of probiotics (Lactobacillus rhamnosus GG (LGG) or Lactobacillus acidophilus (LA)) supplementation on host protection
as a thyroid hormone receptor (TRβ) antagonist in cell-based luciferase reporter gene (CALUX) assay

Biochem/physiol Actions

Deoxynivalenol (DON) blocks the synthesis of DNA and RNA by inhibiting the process of translation.

UPC:: 51422305
Condition:: New
Weight:: 1.00 Ounces
HazmatClass:: No
WeightUOM:: LB
MPN:: D0156-5MG

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