DEXAMETHASONE 21-PHOSPHATE DISODIUM (C15-1225-010)

Catalog No.: C15-1225-010
Mfr. No.: D1159-5G
Mfr. Name: Sigma-Aldrich
Qty/UOM: 5
UOM: GR

Price: $2,265.73

List Price: $2,517.48

Application Dexamethasone 21-phosphate disodium salt has been used: as a positive control to study its effects on ocular shedding of herpes simplex virus type 1 (HSV-1) in the induced reactivation (IR) and spontaneous shedding (SS) rabbit models as

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Description
Specifications

Application

Dexamethasone 21-phosphate disodium salt has been used:

as a positive control to study its effects on ocular shedding of herpes simplex virus type 1 (HSV-1) in the induced reactivation (IR) and spontaneous shedding (SS) rabbit models
as a receptor analog to study its effects on glucocorticoid receptor activation in suprachiasmatic nuclei (SCN)-lesioned mice
to study its protective effects against cisplatin-induced ototoxicity in the inner ear of guinea pigs

Biochem/physiol Actions

Dexamethasone 21-phosphate (Dex 21-P) is a pro-drug that can undergo dephosphorylation to form dexamethasone with the help of intra-erythrocyte enzymes. It exhibits therapeutic effects against cystic fibrosis and postoperative cataract. Dex 21-P disodium salt is a synthetic adrenal corticosteroid and possesses anti-inflammatory activity.

UPC:: 51422342
Condition:: New
Availability:: 3-5 Days
Weight:: 1.00 Ounces
HazmatClass:: No
MPN:: D1159-5G
CAS:: 2392-39-4

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