Dexamethasone, 500mg (C08-0505-543)

Dexamethasone is an anti-inflammatory glucocorticoid that induces the production of phospholipase A2 inhibitory protein (lipocortin). It also inhibits induction of nitric oxide synthase (IC50=5 nM). Dexamethasone has been shown to cause reduction in cyclin A and Cdk2 activity, inhibition of G1/S transition in osteoblasts and inhibition of phosphorylation of Rb protein. Dexamethasone has been observed to induce apoptosis in human thymocytes and eosinophils but to inhibit apoptosis in neutrophils. Dexamethasone is an anti-inflammatory glucocorticoid with a range of effects on cell survival, cell signaling and gene expression. It is used to study apoptosis, cell signaling pathways and gene expression. Glucocorticoid is an anti-inflammatory agent. It Regulates T cell survival, growth, and differentiation. It also inhibits the induction of nitric oxide synthase.