General description
Major secretory steroidal product of the adrenal gland. DHEA and its sulfated metabolite, DHEA-S, are negative modulators of GABAA receptors.
Major secretory steroidal product of the adrenal gland. DHEA, and its sulfated metobolite DHEA-S, are negative modulators of GABAA receptors.
Biochem/physiol Actions
Cell permeable: no
Primary Target
Negative modulators of GABAA receptors
Product does not compete with ATP.
Reversible: no
Warning
Toxicity: Standard Handling (A)
Other Notes
Hansen, S.L., et al. 1999. Mol. Pharmacol. 55, 489.
Imamura, M., and Prasad, C. 1998. Biochem. Biophys. Res. Commun.243, 771.
Majewska, M.D., et al. 1990. Brain Res.526, 143.
Legal Information
CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany
- UPC:
- 51182012
- Condition:
- New
- Availability:
- 3-5 Days
- Weight:
- 1.00 Ounces
- HazmatClass:
- No
- MPN:
- 252805-10GM
- CAS:
- 53-43-0