Application
Automated Boc protection and deprotection can be done using Synple Automated Synthesis Platform (SYNPLE-SC002), Boc protection cartridges ((SYNPLE-B001), (SYNPLE-B002), and Boc deprotection cartridges (SYNPLE-B011)
Di-tert-butyl dicarbonate (Boc anhydride) can be used:
- As a reagent to introduce Boc protecting group for the amine functionalities.
- To prepare tert-butyl ethers and Boc-alcohols in presence of Lewis acid catalyst.
- As a carboxylating agent for the preparation of a variety of tert-butyl carboxylates.
- For the conversion of amines to corresponding isocyanates, carbamates and urea derivatives.
- As a coupling reagent for anchoring various carboxylic acids to hydroxymethylated resins.
- To synthesize quinolinones and 2-(pseudo)haloquinolines from 2-alkenylanilines in presence of DMAP as a catalyst.
Reagent for the introduction of the Boc protecting group.
Warning
Hydrolyzes to t-butanol and CO2; causes internal pressure in bottle if exposed to moisture.
Legal Information
ReagentPlus is a registered trademark of Sigma-Aldrich Co. LLC
- UPC:
- 12142201
- Condition:
- New
- Weight:
- 1.00 Ounces
- HazmatClass:
- No
- WeightUOM:
- LB
- MPN:
- 361941-25G