DIAPOCYNIN (C005B-312771)

Catalog No.: C005B-312771
Mfr. No.: SML0927-5MG
Mfr. Name: Sigma-Aldrich
Qty/UOM: 5
UOM: MG

Price: $214.26

List Price: $238.07

Biochem/physiol Actions Diapocynin is a covalent dimer of apocynin, and a functional metabolite of the same. It is generated by neutrophil activation via myeloperoxidase-mediated oxidation.

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Description
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Biochem/physiol Actions

Diapocynin is a covalent dimer of apocynin, and a functional metabolite of the same. It is generated by neutrophil activation via myeloperoxidase-mediated oxidation. Studies show that diapocynin has greater neuroprotection compared to apocynin.

Diapocynin, a proposed NADPH oxidase (NOX) inhibitor, is an anti-inflammatory and antioxidant agent. Diapocynin attenuates oxidative damage and neuroinflammatory responses in animal model of ParkinsonÃ¢â‚¬Â²s disease. Diapocynin reverses deficient motor coordination in LRRK2R1441Gtg mice of PD.

UPC:: 51171639
Condition:: New
Availability:: 3-5 Days
Weight:: 1.00 Ounces
HazmatClass:: No
MPN:: SML0927-5MG
CAS:: 29799-22-2

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