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dibenzocyclooctyne-maleimide (c15-1308-681)

DIBENZOCYCLOOCTYNE-?MALEIMIDE FOR COPPER-FREE CLICK CHEMISTRY (C005B-232919)

Catalog No.
C005B-232919
Mfr. No.
760668-1MG
Mfr. Name
Sigma-Aldrich
Qty/UOM
1
UOM
MG
Price: $99.66
List Price: $110.74

Application Maleimide functionalized cyclooctyne derivative for incorporation of the cyclooctyne moiety into thiol containing compounds or biomolecules. Cyclooctynes are useful in strain-promoted copper-free azide-alkyne cycloaddition reactions.

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Application

Maleimide functionalized cyclooctyne derivative for incorporation of the cyclooctyne moiety into thiol containing compounds or biomolecules. Cyclooctynes are useful in strain-promoted copper-free azide-alkyne cycloaddition reactions. This dibenzocyclooctyne will react with azide functionalized compounds or biomolecules without the need for a Cu(I) catalyst to result in a stable triazole linkage.

Applications Include:

  • Protein-peptide conjugates
  • Antibody-enzyme or antibody-drug conjugates
  • Protein or peptide-oligonucleotide conjugates
  • Surface modification

Molecular Weight: 427.45. Empirical Formula: C25H21N3O4. Quality Level: 100. form: solid. reaction suitability: reaction type: click chemistry, reagent type: cross-linking reagent. functional group: maleimide. storage temp.: −. 20°C. SMILES string: O: C(N1CCC(NCCC(N2CC3: C(C: CC: C3)C#CC4: C2C: CC: C4): O): O)C: CC1: O. InChI: 1S/C25H21N3O4/c29-22(14-16-27-23(30)11-12-24(27)31)26-15-13-25(32)28-17-20-7-2-1-5-18(20)9-10-19-6-3-4-8-21(19)28/h1-8,11-12H,13-17H2,(H,26,29). InChI key: NHFQNAGPXIVKND-UHFFFAOYSA-N. Pictograms: GHS09. Signal Word: Warning. Hazard Statements: H400. Precautionary Statements: P273. Hazard Classifications: Aquatic Acute 1. Storage Class Code: 11 - Combustible Solids. WGK: WGK 3. Flash Point(F): Not applicable. Flash Point(C): Not applicable.
UPC:
12352200
Condition:
New
Availability:
3-5 Days
Weight:
1.00 Ounces
HazmatClass:
No
MPN:
760668-1MG

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