General description
DBCO-NHS ester is commonly used in bioconjugation. It consists of an NHS ester that reacts with primary amines on biomolecules and an alkyne group that allows for a specific reaction with molecules containing azides. This reaction is carried out through a copper-free click chemistry process called strain-promoted alkyne-azide cycloaddition.
Application
Dibenzocyclooctyne-N-hydroxysuccinimidyl ester is commonly used:
- In the modification and labeling of biomolecules such as antibodies and streptavidin by introducing DBCO groups onto their surfaces
- As a cross linker to conjugate peptide antigens onto the surface of poly(lactic-co-glycolic acid) (PLGA) nanoparticles
- UPC:
- 51282613
- Condition:
- New
- Weight:
- 1.00 Ounces
- HazmatClass:
- No
- WeightUOM:
- LB
- MPN:
- 761524-5MG
