Application
Water soluble succinimidyl ester/NHS functionalized cyclooctyne derivative for incorporation of the cyclooctyne moiety into amine containing compounds or biomolecules. Cyclooctynes are useful in strain-promoted copper-free azide-alkyne cycloaddition reactions. This dibenzocyclooctyne will react with azide functionalized compounds or biomolecules without the need for a Cu(I) catalyst to result in a stable triazole linkage.
Dibenzocyclooctyne-sulfo-N-hydroxysuccinimidyl ester may be used for the covalent modification of nano-sized metal-organic frameworks (NMOFs) with nucleic acids via click chemistry during the synthesis stimuli-responsive DNA-gated NMOFs. These NMOFs can act as carriers of a fluorescent agent or anticancer drug, making them highly useful in targeted drug release system.
Molecular Weight: 532.50. Empirical Formula: C25H21N2NaO8S. Quality Level: 100. form: solid. reaction suitability: reaction type: click chemistry, reagent type: linker. mp: 240-260 . °C. storage temp.: −. 20°C. SMILES string: O: C(CCCCC(ON(C(CC1S(: O)(O[Na]): O): O)C1: O): O)N2CC3: C(C: CC: C3)C#CC4: C2C: CC: C4. InChI: 1S/C25H22N2O8S.Na/c28-22(11-5-6-12-24(30)35-27-23(29)15-21(25(27)31)36(32,33)34)26-16-19-9-2-1-7-17(19)13-14-18-8-3-4-10-20(18)26. /h1-4,7-10,21H,5-6,11-12,15-16H2,(H,32,33,34). /q. +1/p-1. InChI key: QXKHPYSXPCJSPR-UHFFFAOYSA-M. Storage Class Code: 11 - Combustible Solids. WGK: WGK 3. Flash Point(F): Not applicable. Flash Point(C): Not applicable.- UPC:
- 51283919
- Condition:
- New
- Weight:
- 1.00 Ounces
- HazmatClass:
- No
- WeightUOM:
- LB
- MPN:
- 762040-50MG
