Diethyl Pyrocarbonate has been shown to inhibit ryanodine binding to ryanodine/Ca2+ receptor channels in skeletal muscle in a dose- and time-dependent manner and increases the Ca2+ permeability of SR vesicles. This compound could be useful for specific inactivation of nucleases during isolation of undegraded polynucleotides. Diethyl Pyrocarbonate also inhibits PAF Acetylhydrolase (platelet-activating factor acetyl hydrolase), and has been used as a probe for the topography of 5.8S rRNA in yeast ribosomes.Utilized as an antimicrobial additive, a ribonuclease inhibitor, a histidine residue modifier, and as a reagent for conversion of imines to carbamates. Modification reagent for His and Tyr residues in proteins. Robust probe for structural disruptions in dsDNA, reacting with fully or partially unstacked bases. Specification: 0.98 MDL Number: MFCD00009106 Molecular Formula: C6H10O5 Molecular Weight: 162.14 EC Number: 216-542-8 PubChem CID: 3051 Isomeric SMILES: CCOC(=O)OC(=O)OCC Beilstein Registry Number: 637031 Related Documents: https://ald-pub-files.oss-cn-shanghai.aliyuncs.com/aladdinsci/pdp/sds/1/D105557-SCI_dbe2f18146b5f4089e6775d6efde2a4a.pdf
- UPC:
- 12352200
- Condition:
- New
- Availability:
- 1 day
- Weight:
- 1.45 Ounces
- HazmatClass:
- No
- WeightUOM:
- LB
- MPN:
- D105557-5g
- CAS:
- 1609-47-8
- Product Size:
- 5g
- Hazard Statement Codes:
- H302:H315:H319:H335
- Precautionary Statement Codes:
- P261:P305+P351+P338
