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Diethylstilbestrol (C15-1248-975)

Catalog No.
C15-1248-975
Manufacturer No.
D4628-25G
Manufacturer Name
Sigma-Aldrich
Quantity
25
Unit of Measure
GR
Price: $1,697.80
List Price: $1,886.45

Application Diethylstilbestrol has been used: to evaluate the estrogenic activity of diethylstilbestrol by quantitating the expression levels of endogenous estrogen-regulated marker genes to evaluate the estrogenic, androgenic and toxicity

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Application

Diethylstilbestrol has been used:

  • to evaluate the estrogenic activity of diethylstilbestrol by quantitating the expression levels of endogenous estrogen-regulated marker genes
  • to evaluate the estrogenic, androgenic and toxicity responses in bioluminescent yeast bioreporter assay (BLYES)
  • to detect its effect on the proliferation and tyrosinase activity of melanocytes

Biochem/physiol Actions

Diethylstilbestrol is a synthetic estrogen with carcinogenic properties. Causes renal clear-cell carcinoma in Syrian hamster. In humans it causes increased risk of breast cancer, clear cell adenocarcinoma (CCA) of the vagina and cervix, and reproductive anomalies. Used in the treatment of prostate cancer to block the production of testosterone.

UPC:
51182601
Condition:
New
Weight:
1.00 Ounces
HazmatClass:
No
WeightUOM:
LB
MPN:
D4628-25G


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