Skip to main content

Dihydrotanshinone I (C15-1285-559)

Catalog No.
C15-1285-559
Manufacturer No.
D0947-50MG
Manufacturer Name
Sigma-Aldrich
Quantity
50
Unit of Measure
MG
Price: $1,011.43
List Price: $1,123.81

DihydrotanshinoneI (DHTS) is a tanshinone derivative which is a soluble diterpene quinone pigment of danshen. Application Dihydrotanshinone I (DHTS) has been used: to study its cytocidal effects on chemosensitive ovarian cancer cells with or

Enjoy exclusive benefits including discounted pricing on orders by contacting our Sales Executives to open an account.

Adding to cart… The item has been added

General description

DihydrotanshinoneI (DHTS) is a tanshinone derivative which is a soluble diterpene quinone pigment of danshen.

Application

Dihydrotanshinone I (DHTS) has been used:

  • to study its cytocidal effects on chemosensitive ovarian cancer cells with or without platinum-based chemotherapy
  • as a treatment to study its inhibitory effects on triple-negative breast cancer cells growth by modulating epithelial-mesenchymal transition (EMT) markers
  • as a potential SARS-CoV-2 papain-like protease (PLpro) inhibitor
  • as a human antigen R (HuR) inhibitor to study its role in Th17 cell differentiation related to autoimmune neuroinflammation
  • as a reference standard to analyze Salvia miltiorrhiza Bunge extract (SME) components using high-performance liquid chromatography(HPLC)

Biochem/physiol Actions

Dihydrotanshinone Iis a potent anti-cancer agent with its cytotoxic, apoptosis, cell cycle arresteffects and inhibition of angiogenesis, and metastasis in cancer cells. Italso exerts cardiovascular and cerebrovascular protective effects. DHTS isan anti-inflammatory, anti-ischemia-reperfusion (I/R), anti-allergic,anti-Alzheimer’s disease properties. It is also effective againstdrug-resistant cancer cells.

Tanshinone extracted from a herb, Salvia miltiorrhiza, commonly used in Chinese traditional medicine. A significant decrease in tumor growth was observed using dihydrotanshinone I and irradiation treatment with mouse xenograft model.

UPC:
51182012
Condition:
New
Weight:
1.00 Ounces
HazmatClass:
No
WeightUOM:
LB
MPN:
D0947-50MG


Cenmed Satisfaction Guarantee

At Cenmed, your confidence and satisfaction are paramount. We guarantee the quality and reliability of our extensive range of clinical and laboratory supplies. If you're not completely satisfied with your purchase, we offer a straightforward return process and dedicated support to resolve your concerns promptly. Our commitment ensures that you can order with confidence, knowing that Cenmed is dedicated to superior service and customer satisfaction. Trust us to meet your needs with every order, backed by our promise of excellence. Learn more in Help & FAQs.


"Cenmed provides me access to the same products/services normally reserved for much larger labs than mine. I was presently surprised by their product offering."

LAB DIRECTOR


"We utilized Cenmed's capabilities for a variety of projects around the world. They are a valued partner and supplier."

PHARMACEUTICAL SUPPLY CHAIN LEADER


"The reps are very good at finding products for customers in this period of supply chain issues."

SCOTT BEHMAN


"Your customer service has been excellent and makes me excited about purchasing with Cenmed in the future!!"

PROCUREMENT + BILLING COORDINATOR AT PHARMA.