A pan-CDK inhibitor (IC50s = 3, 1, 1, and 4 nM for CDK1, CDK2, CDK5, and CDK9, respectively) that inhibits DNA synthesis in A2780 ovarian cancer cells (IC50 = 4 nM); 5 mg/kg prevents tumor growth by 50% in an A2780 ovarian carcinoma mouse xenograft model; active against a broad spectrum of human tumor cell lines in vitro (IC50s = 7-17 nM).
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- UPC:
- 51111758
- Condition:
- New
- Availability:
- 3 Days
- Weight:
- 1.00 Ounces
- HazmatClass:
- No
- WeightUOM:
- LB
- MPN:
- 14707-5
- CAS:
- 779353-01-4
- Model Number:
- C823R11
- Temperature Control Device:
- Yes