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Diosmetin (C15-1245-871)

Catalog No.
C15-1245-871
Manufacturer No.
D7321-10MG
Manufacturer Name
Sigma-Aldrich
Quantity
10
Unit of Measure
MG
Price: $210.86
List Price: $234.29

Diosmetin is a methylated aglycone flavone of diosmin. It is present abundantly in citrus fruits, Olea europaea L.

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General description

Diosmetin is a methylated aglycone flavone of diosmin. It is present abundantly in citrus fruits, Olea europaea L. (olive tree) leaves, and in the legume of Acacia farnesiana tree.

Application

Diosmetin has been used to test its protective effects on chronic stress memory and cognitive impairment in mice model.

Biochem/physiol Actions

Diosmetin exhibits anti-inflammatory, anti-cancer, antimicrobial, phytoestrogenic, and neuroprotective properties. It displays cytoprotective effects against lipopolysaccharide (LPS)-induced acute lung injury (ALI) by inhibiting nucleotide-binding domain (NOD)-like receptor protein 3 (NLRP3) inflammasome and activating nuclear factor erythroid 2–related factor 2 (Nrf2).

Flavonoid from Citrus limon. Antioxidant. Inhibits carcinogen activation by inhibiting the CYP1A1 enzyme.

UPC:
51145201
Condition:
New
Weight:
1.00 Ounces
HazmatClass:
No
WeightUOM:
LB
MPN:
D7321-10MG


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