InformationDKM 2-93 DKM 2-93 is a relatively selective lead inhibitor of ubiquitin-like modifier activating enzyme 5 (UBA5) .TargetsUBA5In vitroDKM 2-93 not only impairs pancreatic cancer cell survival in PaCa2, but also Panc1 cells with 50 % effective concentration values of 90 and 30 μM, respectively.In vivoDKM 2-93 daily treatment significantly impairs tumor growth of PaCa2 cells in vivo in tumor xenograft studies in immune-deficient mice without causing any weight loss or overt toxicity.Cell Research(from reference)Cell lines：PaCa2 and Panc1 pancreatic cancer cells Incubation Time：48 h. Specification: 0.99 Molecular Formula: C11H14ClNO3 Molecular Weight: 243.69 PubChem CID: 2392259 Isomeric SMILES: COC1=C(C=C(C=C1)CNC(=O)CCl)OC Related Documents: https://ald-pub-files.oss-cn-shanghai.aliyuncs.com/aladdinsci/pdp/sds/1/D413345-SCI_008d29446be01e6462b42ea76a871789.pdf
- UPC:
- 51111703
- Condition:
- New
- Availability:
- 2 weeks
- Weight:
- 0.98 Ounces
- HazmatClass:
- Yes
- WeightUOM:
- LB
- MPN:
- D413345-500mg
- CAS:
- 65836-72-8
- Health Hazards:
- Toxic
- Product Size:
- 500mg
- Hazard Statement Codes:
- H301:H311:H331:H341
- Precautionary Statement Codes:
- P201:P202:P261:P264:P270:P271:P280:P310:P330:P361:P302+P352:P304+P340:P308+P313:P405:P403+P233:P501
