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dl-beta-hydroxybutyric acid sodium salt (c15-1216-775)

DL-beta-Hydroxybutyric acid sodium salt (C15-1216-775)

Catalog No.
C15-1216-775
Manufacturer No.
H6501-25G
Manufacturer Name
Sigma-Aldrich
Quantity
25
Unit of Measure
GR
Price: $546.86
List Price: $607.62

Application DL -β-Hydroxybutyric acid sodium salt has been used: as a standard for quantifying blood plasma and milk β-hydroxybutyric acid in Danish Jersey cows to investigate its anticonvulsant effects in epilepsy induced rats to induce

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Application

DL-β-Hydroxybutyric acid sodium salt has been used:

  • as a standard for quantifying blood plasma and milk β-hydroxybutyric acid in Danish Jersey cows
  • to investigate its anticonvulsant effects in epilepsy induced rats
  • to induce hyperketonemia in Holstein dairy cows

Biochem/physiol Actions

β-Hydroxybutyric acid is a ketone body present in the rumen epithelium of liver cells. Its interconversion to acetoacetate influences the acid-base balance and is coupled NADH generation from (nicotinamide adenine dinucleotide) NAD+, measured fluorimetrically. A high plasma level of β-hydroxybutyric acid is implicated in diabetic ketoacidosis. It traverses the blood-brain barrier as a monocarboxylic acid. β-Hydroxybutyric acid may play a protective role in dopaminergic neurodegeneration in Parkinson′s disease model. β-Hydroxybutyric acid is a ligand for G protein-coupled receptor(GPR109A) and favors inhibition of secretion, transcription and translation of growth hormone (GH) and prolactin (PRL) gene in cow anterior pituitary cells (DCAPCs).

UPC:
51132301
Condition:
New
Weight:
1.00 Ounces
HazmatClass:
No
WeightUOM:
LB
MPN:
H6501-25G


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