Dithiothreitol (DTT), a thiol group protectant, is an excellent reagent for preventing the oxidation of SH groups in proteins. DTT solution is a potent and versatile disulfide-reducing agent. It reduces a disulfide bond by forming a six-membrane ring and initiating a thiol-disulfide interchange.Application:DL-dithiothreitol solution has been used:in the treatment of intestinal explantsin homogenate preparation of gill cells for enzymatic assaysin protein electrophoresis for western blottingin transglutaminase activityin sample buffer for SDS-PAGEin Western Blot, as a lysis buffer component for single-nucleus RNA-sequencingas a component of protein extraction buffer for cell lysis
Specification: BioUltra, for molecular biology, ~1 M in H2O
MDL Number: MFCD00004877
Molecular Formula: C4H10O2S2
Molecular Weight: 154.25
EC Number: MFCD00004877
PubChem CID: 446094
Isomeric SMILES: C([C@H]([C@@H](CS)O)O)S
Beilstein Registry Number: 1719760
- UPC:
- 41116012
- Condition:
- New
- Availability:
- 4-8 weeks
- Weight:
- 0.09 Ounces
- HazmatClass:
- No
- WeightUOM:
- LB
- MPN:
- D755755-10ml
- CAS:
- 3483-12-3
- Product Size:
- 10ml
- Hazard Statement Codes:
- H318:H302:H335:H319:H315