General description
Caged Ca2+ chelator that undergoes a major and rapid decrease in Ca2+-binding affinity upon photolysis. Can be microinjected or permeabilized into cells. May also be useful as a caged Mg2+ chelator. Kd (Ca2+) = 5 nM; Kd (Mg2+) = 2-5 µM.
Caged Ca2+ chelator that undergoes a major and rapid decrease in Ca2+-binding affinity upon photolysis. Can be microinjected or used with permeabilized cells. May also be useful as caged Mg2+ chelator. Kd (Ca2+) = 5 nM; Kd (Mg2+) = 2-5 µM.
Warning
Toxicity: Standard Handling (A)
Reconstitution
Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
Other Notes
Mulkey, R.M., and Zucker, R.S. 1993. J. Physiol. 462, 243.
Zucker, R.S. 1993. Cell Calcium 14, 87.
McCray, J.A., et al. 1992. Biochemistry31, 8856.
Delaney, K.R., and Zucker, R.S. 1990. J. Physiol.426, 473.
Kaplan, J.H., and Ellis-Davies, G.C. 1988. Proc. Natl. Acad. Sci. USA85, 6571.
Morad, M., et al. 1988. Science241, 842.
Legal Information
CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany
Molecular Weight: 561.32. Empirical Formula: C18H19N3O12 · 4Na. Quality Level: 100. Assay: ≥. 93% (HPLC). form: solid. reaction suitability: reagent type: chelator. manufacturer/tradename: Calbiochem®. . storage condition: OK to freeze, desiccated (hygroscopic), protect from light. color: orange. solubility: water: 100 . mg/mL. shipped in: wet ice. storage temp.: −. 20°C. Storage Class Code: 11 - Combustible Solids. WGK: WGK 1. Flash Point(F): Not applicable. Flash Point(C): Not applicable.- UPC:
- 12352107
- Condition:
- New
- Weight:
- 1.00 Ounces
- HazmatClass:
- No
- WeightUOM:
- LB
- MPN:
- 317210-5MG