General description
DMT-2′Fluoro-dA(bz) Phosphoramidite is a 2′Fluoro phosphoramidite that is used to synthesize oligonucleotides that are more thermally stable and provide increased nuclease resistance.
Its key features include,
- Can be employed together with DNA or RNA phosphoramidites
- Recommended deprotection conditions are 8 hours at 55 °C using concentrated ammonia solution, or with AMA for 10 minutes at 65 °C
- Synthesis of 2′Fluoro oligonucleotides is similar to standard DNA synthesis but requires an elongated coupling time (recommended is 3 minutes compared to 90 seconds for DNA monomers)
- Consistent lot-to-lot high purity and performance
- Manufactured under a certified ISO 9001 quality system
base protecting group: benzoyl
2' protecting group: fluoro
5' protecting group: DMT
deprotection: fast/standard. storage temp.: −. 20°C. SMILES string: CC(C)N(C(C)C)P(OCCC#N)O[C@H]([C@H](O1)COC(C2: CC: C(OC)C: C2)(C3: CC: C(OC)C: C3)C4: CC: CC: C4)[C@@H](F)[C@@H]1N5C6: NC: NC(NC(C7: CC: CC: C7): O): C6N: C5. InChI: 1S/C47H51FN7O7P/c1-31(2)55(32(3)4)63(60-27-13-26-49)62-42-39(61-46(40(42)48)54-30-52-41-43(50-29-51-44(41)54)53-45(56)33-14-9-7-10-15-33)28-59-47(34-16-11-8-12-17-34,35-18-22-37(57-5)23-19-35)36-20-24-38(58-6)25-21-36/h7-12,14-25,29-32,39-40,42,46H,13,27-28H2,1-6H3,(H,50,51,53,56)/t39-,40-,42-,46-,63?/m1/s1. InChI key: VCCMVPDSLHFCBB-MSIRFHFKSA-N. Storage Class Code: 11 - Combustible Solids. WGK: WGK 3. Flash Point(F): Not applicable. Flash Point(C): Not applicable.
- UPC:
- 51332878
- Condition:
- New
- Weight:
- 1.00 Ounces
- HazmatClass:
- No
- WeightUOM:
- LB
- MPN:
- A211200-500G