General description
DMT-2′O-TBDMS-rU Phosphoramidite belongs to the group of 2′O-TBDMS RNA Phosphoramidites.
Application
RNA interference (RNAi) has become a popular tool for the sequence-specific inhibition of gene expression and can be used in target validation and other drug development techniques. The most convenient method to provide sequence-specific RNA oligonucleotides is a chemical synthesis on a solid support with RNA phosphoramidites and RNA CPG, analogous to DNA synthesis.
Features and Benefits
- Industry-standard 2′O-TBDMS protective group
- Consistent lot-to-lot purity and performance
- Compatible with deprotection methods based on methylamine or AMA
- Standard RNA phosphoramidites provide excellent coupling results when used with ETT or BTT as activator; best results are obtained with Activator 42
- Capping with standard acetic anhydride capping reagent rather than with Fast Deprotection Cap A
- Manufactured under a certified ISO 9001 quality system
Other Notes
The unique properties of RNA have stimulated the development of a variety of applications in diagnostics and therapeutics, as well as in basic molecular biology research where RNA can be used as:
- Catalytic agents (ribozymes)
- Affinity ligands (aptamers)
- Agents to induce gene silencing (RNA interference)
Shipping Information:
Hazmat Fee: $65.00 + applicable shipping charges are added after the order is placed.
More Information: https://cenmed.com/shipping-returns
- UPC:
- 51313435
- Condition:
- New
- Availability:
- 3-5 Days
- Weight:
- 1.00 Ounces
- HazmatClass:
- Yes
- MPN:
- U211000-100G
- CAS:
- 118362-03-1
