DN02 is a potent, selective BRD8 bromodomain probe. DN02 has exhibits high affinity for the BRD8(1) ( K i =32 nM), which is 30-fold more affinity than BRD8 (2) ( K i ＞1000 nM).Appearance:SolidIn Vitro:DN02 has (1 nM-100 μM) low nM AlphaScreen with IC 50 value of 48 nM, with high selectivity over BRD9 and BRD4 in biochemical AlphaScreen assays. DN02 (32 nM) has minimal off-target engagement across the bromodomain family, with modest activity againsBiological Activity:DN02 is a potent, selective BRD8 bromodomain probe. DN02 has exhibits high affinity for the BRD8(1) ( K i =32 nM), which is 30-fold more affinity than BRD8 (2) ( K i ＞1000 nM). Specification: 0.99 Molecular Formula: C22H24FN3O3 Molecular Weight: 397.44
- UPC:
- 12352005
- Condition:
- New
- Availability:
- 8-12 weeks
- Weight:
- 1.09 Ounces
- HazmatClass:
- No
- WeightUOM:
- LB
- MPN:
- D658743-10mg
- Product Size:
- 10mg
